This is an old, favorite video of mine that popped into my head recently.
It features singer and songwriter Bobby McFerrin, best known for the song, “Don’t Worry, Be Happy.”
McFerrin took to a stage and almost like magic, turns the viewing audience into a giant musical instrument that he proceeds to play.

Truthfully, I don’t know if there is a practical application for this in escape room or immersive game design, but I thought that it might inspire something in someone. Plus, it’s just a cool video.